Genotyping Allele-Specific Copy Number Variants Using Pangenomes
Explore allele-specific copy number variant genotyping using pangenomes. Learn advanced techniques for analyzing complex genomic variations in human populations.
Computational Methods for Modeling and Analyzing Epigenomic Data - CGSI 2023
Explore computational methods for modeling and analyzing epigenomic data, focusing on chromatin state discovery, genome annotation, and cross-species conservation in functional genomics.
Inference from Single Cell Lineage Tracing Data Generated via Genome Editing
Explore single-cell lineage tracing via genome editing, covering inference methods, design parameters, and data analysis for understanding cellular phylodynamics and evolution.
Leveraging High-throughput Functional Characterization Data to Dissect and Annotate Human Regulatory Regions
Explore high-throughput functional characterization techniques for dissecting and annotating human regulatory regions, leveraging advanced genomic mapping and integrative epigenomic approaches.
Population Genetics in Large Genealogies
Explore population genetics using large genealogies, focusing on data analysis, relationship inference, and historical insights from Quebec's French Canadian population.
Detection of Hard and Soft Sweeps from Population Genomic Data
Explore detection methods for hard and soft selective sweeps in population genomics, focusing on Drosophila studies and statistical approaches.
Biobanks from a Pathologist's Viewpoint - CGSI 2023
Explore biobanks from a pathologist's perspective, focusing on genetic disorders, variant classification, and the interplay between monogenic and polygenic factors in disease expression.
Timewarp: Transferable Acceleration of Molecular Dynamics by Time-Coarsened Dynamics
Explore Timewarp: a transferable method for accelerating molecular dynamics simulations using normalizing flows, enhancing sampling efficiency for equilibrium properties of molecular systems.
Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom
Explore advanced biomolecular modeling using RoseTTAFold All-Atom. Learn to predict and design complex biological assemblies, including proteins, nucleic acids, and small molecules, with applications in drug discovery and synthetic biology.
Timewarp: Transferable Acceleration of Molecular Dynamics by Learning Time-Coarsened Dynamics
Explore accelerated molecular dynamics simulation using Timewarp, a transferable AI method for efficient sampling of molecular systems and discovery of metastable states.
Harmonic Self-Conditioned Flow Matching for Multi-Ligand Docking and Binding Site Design
Explore advanced AI techniques for protein-ligand binding structure generation and binding site design, improving drug discovery and molecular interaction modeling.
PepFlow: Direct Conformational Sampling From Peptide Energy Landscapes
Explore PepFlow, a deep learning approach for direct conformational sampling of peptides. Learn about its modular design, hypernetwork integration, and applications in drug discovery.
Geometric Deep Learning Framework for De Novo Genome Assembly
Explore a novel geometric deep learning framework for de novo genome assembly, enhancing path identification in complex assembly graphs for improved genomic sequence reconstruction.
Binding Affinity Prediction with ML-Based Docking - Lab 2
Explore ML-based docking for binding affinity prediction in drug discovery, featuring insights from experts Stephan Thaler and Cristian Gabellini.
Protein Folding and Design - Day 5
Explore protein folding and design techniques with Alex Tong, delving into advanced machine learning applications for drug discovery and structural biology.
Coarse Grained Biological Systems - Day 2
Explore coarse-grained biological systems in drug discovery with Jacopo Venturin, delving into advanced machine learning applications for pharmaceutical research.
Modeling Population Dynamics - Day 4
Explore population dynamics modeling techniques for drug discovery, focusing on innovative approaches and their applications in pharmaceutical research.
Virtual Screening Techniques for Drug Discovery - Lab 1
Explore virtual screening techniques for drug discovery through hands-on lab exercises guided by industry experts.
Virtual Screening Explanation - Lab 1
Explore virtual screening techniques for drug discovery with experts Lu Zhu and Cas Wognum in this recorded session from the 2024 ML for Drug Discovery Summer School.
Gene Regulatory Network Structure and Perturbation Effects Distribution - Simulation and Analysis
Explore gene regulatory network structure and its impact on perturbation effects. Gain insights into simulating and modeling GRNs for improved understanding of gene expression regulation.
OpenFold: Lessons Learned and Insights from Rebuilding and Retraining AlphaFold2
Explore insights from rebuilding AlphaFold2, including performance analysis, learning mechanisms, and current progress in protein structure prediction.