Large-Scale Inference of Ancestral Recombination Graphs for Genealogy-Based Association of Complex Traits
Explore large-scale inference of ancestral recombination graphs and its application in genealogy-based association of complex traits, advancing genomic research and population genetics.
Quantitative Models of Genetic Variation in Cis-Regulation - 2022
Explore quantitative models of genetic variation in cis-regulation, focusing on haplotype-aware modeling and regulatory effect size quantification in eQTL data.
Determining the Molecular Intermediates Between Genotype and Phenotype
Explore molecular intermediates between genotype and phenotype, focusing on transcription factor binding, Mendelian randomization, and causal network discovery in genomics research.
Understanding GWAS Mechanisms with Transcriptome-Wide Association Studies
Explore GWAS mechanisms through Transcriptome-Wide Association Studies. Learn to identify genetic determinants of chromatin and quantify genetic effects on disease mediated by gene expression levels.
How to Detect Evolution from Microbiome Data
Explore methods for detecting microbial evolution in the gut, examining strain diversity, biogeography, and rapid adaptation. Gain insights into population genetics and its impact on microbiome ecology.
Clonal Hematopoiesis of Indeterminate Potential and DNA Methylation in Aging and Disease
Explore clonal hematopoiesis, DNA methylation's role in aging and disease. Analyze CHIP mutations, epigenome-wide association studies, and their impact on cell fate and disease risk.
Genetics Basis of Depression - CGSI 2022
Explore the genetic foundations of depression, examining recent research findings and their implications for understanding this complex mental health disorder.
On the Number of Genealogical Ancestors Tracing to Source Groups in Admixed Populations
Explore genealogical ancestry in admixed populations through a mechanistic model. Gain insights into African American history and the impact of the Trans-Atlantic Slave Trade on genetic heritage.
Evaluating the Potential Benefits of Embryo Screening Using Polygenic Scores for Multiple Traits
Explore the potential and limitations of embryo screening using polygenic scores for multiple traits. Analyze ethical considerations and scientific challenges in this emerging field of reproductive genetics.
Haplotype Phasing: Methods and Accuracy
Explore haplotype phasing methods and accuracy with Professor Brian Browning. Learn about fast two-stage phasing, integrative estimation, and genotype error impacts on trio-based accuracy.
Integration of Monogenic and Common Variants in Human Disease - CGSI 2022
Explore the integration of monogenic and common variants in human disease, focusing on complex traits, congenital heart defects, and the challenges of phenotyping rare diseases.
Distance-Based Phylogenetics: Past, Present, and Future - CGSI 2022
Explore distance-based phylogenetics' evolution, from theoretical foundations to cutting-edge applications in ecological sample identification and deep learning for phylogenetic placement.
Recent Progress Towards Petabase-Scale Genomics
Explore recent advancements in petabase-scale genomics, focusing on efficient whole-genome assembly techniques and large-scale sequence alignment for viral discovery.
Sardinia Population History and Complex Trait Variation - CGSI 2022
Explore Sardinia's unique genetic history and its impact on complex trait variation, uncovering insights into population dynamics, selection, and disease risk.
Living in the Future of Genomics
Explore cutting-edge genomics research and its future implications with insights from Rayan Chikhi at the Computational Genomics Summer Institute.
Computational Biomedicine: Epigenetics, Liquid Biopsy, and Alternative Polyadenylation Therapy
Explore computational biomedicine, focusing on epigenetics, liquid biopsy, and alternative polyadenylation therapy. Gain insights into cutting-edge research and applications in genomics and cancer detection.
Design, Construction, and Usage of the Draft Pangenome - CGSI 2023
Explore the design, construction, and application of draft pangenomes in genomics. Learn about structural variations, gene expression impacts, and efficient genotyping techniques using cutting-edge pangenome approaches.
From Mutagenic Processes to Mutational Signatures and Back
Explore mutagenic processes and mutational signatures in cancer genomics. Uncover DNA repair contributions, influence networks, and novel approaches to understanding cancer mutational landscapes.
Generating Realistic Chromosome-Scale Simulations for Population Genomics Studies
Explore realistic chromosome-scale simulations for population genomics using advanced tools and techniques. Learn to generate accurate models for genetic studies and research.
BART: A Transcriptional Regulator Prediction Method for Functional Genomics
Explore BART, a powerful method for predicting transcriptional regulators in functional genomics. Learn its applications, underlying algorithms, and impact on gene regulation research.
SwabSeq: Sequencing-based Detection of Pathogens - CGSI 2023
Explore SwabSeq, a sequencing-based method for detecting pathogens like SARS-CoV-2. Learn about its high-throughput capabilities, lean principles for quality improvement, and applications in COVID-19 testing.