Explore the science of sleep in this 28-minute conference talk from GOTO Copenhagen 2018. Delve into the function of sleep, consequences of poor sleep, and how short and long sleep durations relate to poorer health. Learn about chronotypes, the Two Process model, and the neurobiology of wakefulness. Discover the flip-flop switch model, circadian regulation, and the 2017 Nobel Prize-winning research on molecular mechanisms regulating circadian clocks. Examine factors affecting sleep, including light, temperature, and external noise. Investigate sleep changes with age, indicators of hyperarousal in insomnia, and sleep-related breathing disorders. Gain insights into neurological disorders associated with sleep problems and explore the societal and industrial potential for improving sleep. Understand polygraphic measures during wake and sleep, and learn about optimizing machine learning performance for sleep staging.