Explore the fascinating population history and complex trait variation of Sardinia in this 39-minute conference talk by John Novembre, Associate Professor at the University of Chicago. Delve into lessons on human genetic variation and the impact of divergence, gene flow, and selection. Gain insights from multiple research papers covering Sardinian genomic history, genetic changes from the Middle Neolithic to present, autoimmunity risk factors, and height-reducing variants. Discover how this isolated Mediterranean island population provides unique opportunities for understanding human evolution and complex trait genetics.