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#Genetic Variation

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Yale University

The Origin and Maintenance of Genetic Variation - Lecture 6

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Explore genetic diversity's origins through mutations, selection, and recombination. Discover how population size impacts evolution and genetic variation maintenance in different scenarios.
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6 Lesons
48 minutes
On-Demand
Free-Video
University of California, Davis

Introduction to Genomics

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Comprehensive exploration of genomics, covering DNA sequencing, genome assembly, gene editing, epigenomics, RNA-seq, chromatin organization, interaction networks, and genetic variation analysis.
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80 Lesons
18 hours
On-Demand
Free-Video
Santa Fe Institute

The Evolutionary Causes of Quantitative Genetic Variation

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Explore the genetic architecture of quantitative traits, examining how mutation, selection, and drift shape heritable variation. Gain insights into missing heritability and interpret genome-wide association studies findings.
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18 Lesons
1 hour 2 minutes
On-Demand
Free-Video
University of Oxford

Modelling Genes

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Explore genetic variation patterns through mathematical models, examining inheritance, natural selection, and population dynamics to interpret DNA data and understand evolutionary mechanisms.
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21 Lesons
54 minutes
On-Demand
Free-Video
Broad Institute

MPG Primer: Introduction to Fine-Mapping - 2023

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Explore fine-mapping techniques in genetics, covering basic principles, statistical methods, and applications in identifying causal variants for complex traits and diseases.
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1 Lesons
50 minutes
On-Demand
Free-Video
Broad Institute

Medical and Population Genetics Primer: All of Us Research Program - Part 2

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Explore advanced concepts in medical and population genetics, focusing on complex trait analysis, human genetic variation, and cutting-edge sequencing methods.
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1 Lesons
21 minutes
On-Demand
Free-Video
Broad Institute

Advancing the Toolchain for Interpreting Human Genetic Variation Using Deep Learning and Single-Cell Genomics

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Explore deep learning and single-cell genomics tools for interpreting human genetic variation with Oliver Stegle from EMBL and DKFZ.
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1 Lesons
1 hour 4 minutes
On-Demand
Free-Video
Broad Institute

Medical and Population Genetics Primer: All of Us Research Program - Part 1

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Explore the basics of medical and population genetics, covering human genetic variation, genotyping, and DNA sequencing methods in this informative primer series.
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1 Lesons
40 minutes
On-Demand
Free-Video
Broad Institute

Inclusive Genomics: Exploring Genetic Variations in Neglected Populations and Sex Chromosomes

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Explore genetic variations in neglected populations and sex chromosomes with Marla Mendes' insights on inclusive genomics.
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1 Lesons
50 minutes
On-Demand
Free-Video
Broad Institute

gnomAD v4: Behind the Scenes

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Explore the creation, processing, and quality control of gnomAD v4, a comprehensive genomic database, with insights into variant quality and intolerance analysis.
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10 Lesons
40 minutes
On-Demand
Free-Video
MassGeneralHospital

Neurodevelopmental Origin of Childhood Central Nervous System Tumors

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Explore molecular subtypes and genetic variations in childhood brain tumors, focusing on their neurodevelopmental origins.
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1 Lesons
56 minutes
On-Demand
Free-Video
Broad Institute

Tissue-Aware Conservation Inference Toolkit (TACIT) for Relating Enhancer Genetic Variation to Complex Phenotypes

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Explore TACIT, a toolkit for relating enhancer genetic variation to complex phenotypes. Learn about tissue-aware conservation inference and its applications in medical and population genetics.
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1 Lesons
45 minutes
On-Demand
Free-Video
Broad Institute

MPG Primer: STACI - 2023

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Explore STACI, a novel method for analyzing single-cell data to uncover cell type-specific genetic effects on gene expression and disease risk.
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1 Lesons
29 minutes
On-Demand
Free-Video
Broad Institute

MPG Primer: Sequencing and Analysis of Long-Read Whole Genome Data - 2024

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Explore long-read whole genome sequencing and analysis techniques, focusing on advanced methods for medical and population genetics research.
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1 Lesons
49 minutes
On-Demand
Free-Video
Broad Institute

MPG Primer: Introduction to Population Genetics (2024)

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Explore fundamental concepts of population genetics, including genetic variation, inheritance patterns, and evolutionary forces shaping populations.
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1 Lesons
45 minutes
On-Demand
Free-Video
Broad Institute

Genomic Interpretation, seqr and Matchmaker Exchange - MPG Primer 2024

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Explore genomic interpretation techniques, seqr software, and Matchmaker Exchange for advancing genetic research and diagnosis. Learn key tools for analyzing complex genetic data.
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1 Lesons
41 minutes
On-Demand
Free-Video
Broad Institute

Haplotype Assembly Using Short and Long Reads - 2022

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Dive into haplotype assembly techniques using short and long reads. Explore advanced bioinformatics methods for genetic analysis with insights from Ramin Shirali's research at TU Delft.
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1 Lesons
43 minutes
On-Demand
Free-Video
Broad Institute

Statistical Genetics: Importance of Using Globally Representative Data Sets and Inclusive Analytical Methods

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Dive into statistical genetics with Hailiang Huang, exploring the crucial role of globally representative data sets and inclusive analytical methods in research.
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1 Lesons
18 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Genotype Representation Graph: Enabling Efficient Analysis of Biobank-Scale Data

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Dive into efficient analysis of biobank-scale data using Genotype Representation Graphs. Explore innovative methods for estimating coalescence times and inferring whole-genome histories in large population datasets.
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1 Lesons
29 minutes
On-Demand
Free-Video
TEDx

Médecine de Précision - Retour à la Base

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Découvrez comment la génétique moléculaire et la médecine de précision révolutionnent les soins de santé, en mettant l'accent sur l'importance de l'ADN africain pour compléter les connaissances génétiques mondiales.
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13 Lesons
18 minutes
On-Demand
Free-Video
Fields Institute

Drug-Induced Resistance in Cancer Chemotherapy: Darwinian Selection vs Generation of Variation

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Explore mechanisms of drug resistance in cancer treatment, comparing Darwinian selection to variation generation and selection processes in chemotherapy outcomes.
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1 Lesons
28 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Detection of Genetic Variation in Highly Homologous Genes Using Short Read Sequencing

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Explore techniques for detecting genetic variations in highly homologous genes using short read sequencing, focusing on challenges and innovative approaches in computational genomics.
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1 Lesons
30 minutes
On-Demand
Free-Video
Royal Tyrrell Museum of Palaeontology

Ecological Opportunity and Adaptive Radiation of Fanged Frogs in Southeast Asia

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Explore rapid speciation and evolution of fanged frogs in Southeast Asia, focusing on morphological diversity, ecological adaptations, and unique reproductive strategies.
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24 Lesons
47 minutes
On-Demand
Free-Video
Khan Academy

Phases of Meiosis

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Explore the intricate process of meiosis, from prophase to anaphase II, gaining a comprehensive understanding of cell division and genetic variation in reproductive cells.
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5 Lesons
27 minutes
On-Demand
Free-Video
EvoEcoSeminars

Tracking Short-Term Evolution in a Pedigreed Wild Population

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Explore short-term evolution in wild populations through pedigree analysis, examining genetic contributions, selection processes, and life-cycle stages to uncover evolutionary dynamics in nature.
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27 Lesons
54 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Introduction to the Coalescent Theory - Lecture 2

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Explore coalescent theory, population genetics, and evolutionary processes. Covers effective population size, migration, recombination, and linkage disequilibrium. Includes examples and simulations to illustrate key concepts.
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47 Lesons
1 hour 27 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Asexual Adaptation

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Explore asexual adaptation in populations through theoretical frameworks and mathematical models, gaining insights into evolutionary processes and their implications for various biological disciplines.
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1 Lesons
1 hour 26 minutes
On-Demand
Free-Video
Simons Institute

Machine Learning Models of Differential Gene Expression

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Explore deep learning models for predicting regulatory functions from genomic DNA, uncovering mechanisms behind genetic variation's impact on cellular function and gene expression.
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1 Lesons
1 hour 3 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

The Genetic Architecture of Repeated Local vs. Global Adaptation in Plants

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Explore genetic architecture in plant adaptation, focusing on local vs. global patterns. Gain insights into polygenic traits and their role in evolutionary biology.
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1 Lesons
1 hour 33 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Polygenic Adaptation - Lecture 2

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Explore polygenic adaptation in evolutionary biology, integrating diverse perspectives on adaptive dynamics and genetic variation's role in phenotypic traits. Gain insights into quantitative frameworks and empirical data analysis.
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1 Lesons
1 hour 21 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Ecology and Perpetual Evolution in High Dimensions

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Explore ecological dynamics and evolutionary processes in complex, high-dimensional systems. Gain insights into adaptive mechanisms and their impact on biological diversity and ecosystem stability.
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1 Lesons
1 hour 37 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Adaptation to Changing Environments

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Explore genetic mechanisms of adaptation to environmental changes, focusing on polygenic traits and integrating various evolutionary perspectives for a comprehensive understanding.
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1 Lesons
1 hour 31 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Polygenic Adaptation - Lecture 3

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Explore polygenic adaptation in evolutionary biology, integrating diverse perspectives on adaptive dynamics and genetic variation's role in phenotypic traits.
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1 Lesons
1 hour 27 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Mutation and Drift - Lecture 3

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Explore mutation and genetic drift's impact on evolutionary dynamics, focusing on their roles in shaping genetic variation and adaptation in populations.
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1 Lesons
1 hour 36 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Understanding Polygenic Adaptation with Experimental Evolution

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Explore polygenic adaptation through experimental evolution, integrating genetic and phenotypic insights to understand complex trait inheritance and adaptive dynamics in biological systems.
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1 Lesons
1 hour 26 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Polygenic Adaptation - Lecture 4

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Explore polygenic adaptation in evolutionary biology, integrating diverse perspectives on genetic variation and phenotypic traits. Learn about recent insights and quantitative approaches to adaptive dynamics.
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1 Lesons
1 hour 45 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

The Grapheme-Valued Wright-Fisher Diffusion With Mutation by Anita Winter

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Explore grapheme-valued Wright-Fisher diffusion with mutation in population genetics. Gain insights into mathematical models for genetic variation and evolutionary processes.
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1 Lesons
56 minutes
On-Demand
Free-Video
Institut Henri Poincaré

Ecological Chaos and Evolution of Intra-Species Diversity

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Explore ecological chaos and its impact on intra-species diversity evolution, delving into complex interactions shaping biodiversity within populations.
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1 Lesons
24 minutes
On-Demand
Free-Video
National Human Genome Research Institute

History of Genomics and the Human Genome Project

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Explore the history of genomics and the Human Genome Project with NHGRI director Eric Green, highlighting key milestones and their impact on modern genetics and medicine.
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1 Lesons
1 hour 26 minutes
On-Demand
Free-Video
Cambridge University Press

Understanding Genes and Evolution

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Explore the intricacies of genetics and evolutionary processes with author and researcher Kostas Kampourakis in this insightful presentation from the Cambridge Festival 2023.
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1 Lesons
40 minutes
On-Demand
Free-Video
National Human Genome Research Institute

Sequencing Genomes - Journeys in Human Genetics and Genomics Colloquium

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Explore cutting-edge genome sequencing techniques and their impact on human genetics research with NHGRI's Adam Phillippy in this comprehensive presentation.
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1 Lesons
1 hour 31 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Quantitative Models of Genetic Variation in Cis-Regulation - 2022

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Explore quantitative models of genetic variation in cis-regulation, focusing on haplotype-aware modeling and regulatory effect size quantification in eQTL data.
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1 Lesons
52 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Sardinia Population History and Complex Trait Variation - CGSI 2022

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Explore Sardinia's unique genetic history and its impact on complex trait variation, uncovering insights into population dynamics, selection, and disease risk.
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1 Lesons
39 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Genotyping Allele-Specific Copy Number Variants Using Pangenomes

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Explore allele-specific copy number variant genotyping using pangenomes. Learn advanced techniques for analyzing complex genomic variations in human populations.
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1 Lesons
31 minutes
On-Demand
Free-Video
Labroots

Comprehensive Structural Variant Detection: From Mosaic to Population Level

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Explore advanced structural variant detection using Sniffles2, a powerful tool for identifying complex genomic alterations with increased accuracy, speed, and functionality in long-read sequencing data.
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1 Lesons
26 minutes
On-Demand
Free-Video
Labroots

Towards a Comprehensive Variation Benchmark for Medically-Relevant Autosomal Genes

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Explore advancements in genomic benchmarking for medically-relevant autosomal genes. Learn about GIAB consortium's efforts to improve variant calling in challenging genomic regions.
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1 Lesons
23 minutes
On-Demand
Free-Video
Labroots

Application of Long-read Sequencing in Human Genetics

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Explore long-read sequencing's revolutionary impact on human genetics, enabling rapid genome assembly and comprehensive variation detection for enhanced disease understanding.
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1 Lesons
31 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Dissecting the Contribution of the Repeatome to Complex Traits

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Explore the impact of repetitive DNA sequences on complex traits through genome-wide association studies, focusing on short tandem repeats and their role in human phenotypes and gene expression.
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24 Lesons
37 minutes
On-Demand
Free-Video
GOTO Conferences

Deep Learning in Medicine - An Introduction and Applications to Next-Generation Sequencing and Disease Diagnostics

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Exploring deep learning applications in medicine, focusing on genetic variation detection using neural networks and its potential impact on disease diagnostics and genomics.
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26 Lesons
53 minutes
On-Demand
Free-Video
Georgia Tech Research

Creating the Fourth Chapter of Human Genomics

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Explore the future of human genomics with Dr. Eric Green as he discusses the fourth chapter of this revolutionary field and its potential impact on medicine and society.
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1 Lesons
1 hour 8 minutes
On-Demand
Free-Video
Manolis Kellis

Disease Mechanism and Genetic Analysis: From GWAS to Biological Insights - Lecture 18

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Delve into disease mechanisms through genetic analysis, exploring GWAS studies, trait heritability, and the FTO obesity locus while mastering techniques for understanding complex biological pathways and genetic variations.
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21 Lesons
1 hour 28 minutes
On-Demand
Free-Video
Johns Hopkins Medicine

Genetic Variation in the Gene Encoding ER-Stress Kinase PERK - Altered Stress Tolerance in Neurons and Glia

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Explore genetic variations in PERK and their impact on neuronal and glial stress tolerance, potentially contributing to HIV-associated CNS changes.
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1 Lesons
1 hour 4 minutes
On-Demand
Free-Video
Denver Museum of Nature & Science

Scientists in Action: Mighty Mutations and Dazzling DNA - Understanding Human Genetic Variation

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Explore the fascinating world of genetics with a genomics scientist, discovering how DNA mutations shape human uniqueness and our surprising genetic connections to other species.
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1 Lesons
46 minutes
On-Demand
Free-Video