Computational Systems Biology
Explore computational approaches to model and analyze biological systems, from network biology to dynamic modeling, with hands-on labs using MATLAB and other tools.
Sloppy Models, Differential Geometry, and Why Science Works
Explore how complex systems can be modeled despite parameter uncertainties, using differential geometry to understand 'sloppiness' and its implications for scientific comprehension and prediction.
The Laws of Life, Time and Chance
Explore the intersection of physics and biology, uncovering mathematical frameworks for understanding life, time, and probability. Discover how chance governs cellular behavior and impacts complex biological phenomena.
Meet Your Inner Microbial Zoo - Understanding the Human Microbiome
Explore the human microbiome's impact on health, development, and immunity. Learn about metagenomics, predictive modeling, and future clinical applications in this fascinating lecture on our inner microbial ecosystem.
A New Thermodynamics of Biochemistry - Part 1
Exploring the intersection of thermodynamics and biology to better understand cellular processes and their implications for sustainability and economics.
The Laws of Sensitivity for Small Nonequilibrium Systems
Explore laws constraining sensitivity in small, nonequilibrium systems. Uncover mechanisms behind biochemical switches, sensors, and molecular discrimination, with implications for gene regulation models.
What is Lyfe? Towards a Biology of Context and Complexity
Exploring a multidimensional view of biology beyond genomics, emphasizing history, context, environment, and narrative to reframe our understanding of life and its complexities.
How Experiment and Theory Have Informed Each Other in Neuroscience - Past 25 Years
Explore a captivating lecture by 2024 Nobel Prize in Physics winner John Hopfield, delivered at the Kavli Institute for Theoretical Physics in 2010. Delve into the intricate relationship between experiment and theory in neuroscience over the past quarter…
Guiding Model-Driven Combination Dose Selection Using Multi-Objective Synergy Optimization
Explore a 26-minute conference talk by Jana Gevertz from The College of New Jersey on model-driven combination dose selection using multi-objective synergy optimization. Delivered as part of the Frontiers in Computational and Mathematical Medicine series…
Local vs. Nonlocal Models for Mitochondria Swelling
Explore local versus nonlocal models for mitochondria swelling in this 30-minute conference talk by Messoud Efendiev from Helmholtz Zentrum München. Delve into the mathematical and computational approaches used to study mitochondrial dynamics, focusing o…
Mathematical Modelling of Oncolytic Virotherapy
Explore the intricacies of mathematical modeling in oncolytic virotherapy through this 48-minute lecture by Thomas Hillen from the University of Alberta. Delve into advanced concepts at the intersection of computational and mathematical medicine, with a…
Curing Cancer with Calculus - Lecture 3
Explore the intersection of mathematics and cancer research in this 58-minute distinguished lecture by Helen Byrne from the University of Nottingham and University of Oxford. Delve into the innovative application of calculus in oncology as part of the Fr…
Insights into B Cell and Antibody Kinetics Against SARS-CoV-2 Variants Using Mathematical Modelling
Explore the dynamics of B cell and antibody responses to SARS-CoV-2 variants through mathematical modeling in this 18-minute conference talk. Gain valuable insights as speaker Suzan Farhang-Sardroodi from the University of Toronto presents her research f…
Mathematical and Computational Medicine: From Data to Models and Back
Explore the intersection of mathematics, computation, and medicine in this 16-minute conference talk by Andrew Dhawan from Cleveland Clinic. Delve into the dynamic relationship between data and models in the field of mathematical and computational medici…
Computational Modeling of Blood Cancer Evolution and Patient Prognosis
Explore a 47-minute lecture on computational modeling techniques for blood cancer evolution and patient prognosis. Delve into cutting-edge research presented by Thomas Stiehl from RWTH Aachen University as part of the Fields Institute's Thematic Program…
Ecological Niches for the Development of Drug-Induced Resistance
Explore the concept of ecological niches in the context of drug-induced resistance in cancer treatment through this 26-minute lecture by Kasia Rejniak from Moffitt Cancer Center. Delve into the intersection of ecology, evolution, and oncology as part of…
A Mathematical Model of Evolution of Drug-Induced Resistance
Explore a 55-minute lecture on the mathematical modeling of drug-induced resistance evolution, presented by Eduardo Sontag from Northeastern University. Delve into the complex interplay between cancer treatment and the development of drug resistance, as…
Modelling the Impact of Intra-Tumour Heterogeneity on Radiotherapy Outcomes
Explore a 39-minute lecture on the impact of intra-tumour heterogeneity on radiotherapy outcomes, delivered by Giulia Celora from University College London. Delve into the complex world of mathematical oncology as part of the Fields Institute's Thematic…
Mathematical Modeling of Blood Cancer and Premalignancy
Explore a 33-minute lecture on mathematical modeling of blood cancer and premalignancy presented by Morten Andersen and Jordan Snyder from Roskilde University. Delivered on October 3, 2024, as part of the Ecology and Evolution of Cancer series and the Th…
Defining Selection in Somatic Evolution by Modeling Tumor-Stromal Interactions
Explore the complex dynamics of tumor-stromal interactions and their role in somatic evolution through a 35-minute lecture by David Basanta from Moffitt Cancer Center. Delve into the fascinating field of mathematical oncology as part of the Thematic Prog…
Personalized Cancer Care through Digital Twin Technology: Integrating Patient-Specific Data with Quantitative Systems Pharmacology
Explore a cutting-edge lecture on the integration of digital twin technology with quantitative systems pharmacology for personalized cancer care. Delve into the innovative approach presented by Leili Shahriyari from the University of Massachusetts Amhers…