Nanopore Sensing of DNA-Histone Complexes on Nucleosome Arrays
Explore nanopore sensing techniques for analyzing DNA-histone complexes in nucleosome arrays, advancing understanding of chromatin organization and gene regulation.
Protein Search Processes Mediated by Chromatin Topology
Explore protein search processes influenced by chromatin topology, uncovering mechanisms of gene regulation and DNA-protein interactions in the cellular environment.
Super-silencer Perturbation by EZH2 and REST Inhibition Leads to Large Loss of Gene Repression
Explore chromatin organization and gene regulation through EZH2 and REST inhibition, focusing on super-silencer perturbation and its significant impacts.
H3S10p Preserves Interphase Memory by Compaction of Active Chromatin in Mitosis
Explore how H3S10p compacts active chromatin during mitosis, preserving interphase memory. Gain insights into chromatin organization and gene regulation mechanisms.
Constitutional DNA Methylation Testing in the Clinical Setting
Explore DNA methylation testing's clinical applications for diagnosing epigenetic disorders, understanding gene regulation, and enhancing genomic diagnostics.
Gene Regulation in Cellular Senescence
Explore gene regulation in cellular senescence with Prof. Masashi Narita, uncovering key insights on epigenetic aspects and senescence-associated heterochromatic foci (SAHFs).
Towards an Understanding of Chromatin Remodeler Function in Development at Single-Cell Resolution
Explore chromatin regulators' role in mammalian development and human disorders through single-cell analysis of mouse knockouts, uncovering developmental impacts and gene networks.
Designing DNA with Tunable Regulatory Activity Using Discrete Diffusion
Explore DNA Discrete Diffusion (D3) for engineering regulatory DNA sequences with targeted functional activity levels. Learn about its advantages, evaluation metrics, and applications in functional genomics.
Computational Methods for Modeling and Analyzing Epigenomic Data
Explore computational methods for modeling and analyzing epigenomic data, focusing on chromatin state annotation, gene-based modeling, and cross-species conservation in functional genomics.
Dissecting the Gene Regulatory Grammar at a Single Cell Resolution
Explore gene regulatory mechanisms at single-cell resolution. Discover cutting-edge techniques for analyzing multimodal data and constructing regulatory networks in genomics research.
Machine Learning Models for Single Cell and Regulatory Genomics - CGSI 2023
Explore machine learning models for single-cell and regulatory genomics, focusing on recent research and applications in computational biology.
Proto-oncogenes: How They Lead to Cancer - The Biology of Proto-oncogenes
Explore proto-oncogenes and their role in cancer development. Understand the biology behind these genes and their significance in USMLE preparation.
Transcription Factors, General Transcription Factors, and Transcription Factor Networks in Molecular Biology
Explore transcription factors, their general types, and complex networks in molecular biology. Gain insights into gene regulation mechanisms and their importance in cellular processes.
miRNA Export, Transport and Uptake via Extracellular Vesicles in Mammalian Cells
Explore miRNA dynamics in mammalian cells, focusing on export, transport, and uptake through extracellular vesicles. Gain insights from expert Dr. Suvendra Battacharyya.
HyenaDNA: Long-Range Genomic Sequence Modeling at Single Nucleotide Resolution
Explore HyenaDNA: a genomic foundation model using long-range context and single nucleotide resolution. Learn about its design, experiments, and state-of-the-art performance in genomic sequence modeling.
Regulatory Circuitry and Networks - Lecture 7
Explore regulatory circuitry and networks in biological systems, focusing on gene regulation mechanisms and their interconnected pathways.
Regulatory Circuitry - Lecture 6
Explore regulatory circuitry in genomics, uncovering mechanisms of gene expression control and cellular regulation through advanced computational analysis techniques.