Explore the fascinating biological connection between the brain and digestive system in this 50-minute UCLA lecture by gastroenterologist Dr. Emeran Mayer. Delve into the current scientific understanding of the gut microbiome, its functions, and communication methods. Discover how diet impacts brain health, the role of serotonin in gut-brain interaction, and the effects of stress on digestive processes. Learn to interpret bodily signals and "listen to your gut" as Dr. Mayer discusses leaky gut syndrome, food addiction, and obesity. Gain insights into the rapidly evolving field of gut-brain research, including super principle component analysis and controlled clinical trials. Conclude with a Q&A session addressing treatment options and detoxification strategies for maintaining optimal gut health.