Explore the complex relationship between genetics, appetite control, and obesity in this 58-minute lecture by geneticist and neuroscientist Giles Yeo from The Royal Institution. Delve into the biological variations in appetite control and how genetics can be used as a tool to understand them. Learn about the obesity epidemic, its contemporary causes, and the role of genetic makeup in determining why some individuals eat more than others. Discover insights on topics such as leptin, monogenic obesity, mutations, risk scores, and the concept of genetics as a "hand of cards." Gain a deeper understanding of how genes influence body weight and appetite, and explore the interplay between genetic predisposition and lifestyle factors in the development of obesity.