Explore a conference talk on fast structure and positional ortholog searching, as well as viral metagenome assembly, presented by Johannes Söding at the Centre International de Rencontres Mathématiques in Marseille, France. Delve into cutting-edge research at the intersection of AI and mathematical modeling in post-structural genomics. Recorded during the thematic meeting "Interplay between AI and mathematical modelling in the post-structural genomics era" on March 21, 2023, this 29-minute presentation offers valuable insights for researchers and students in bioinformatics, genomics, and computational biology. Access this talk and other presentations by renowned mathematicians through CIRM's Audiovisual Mathematics Library, featuring chapter markers, keywords, abstracts, bibliographies, and Mathematics Subject Classification for enhanced navigation and comprehension.