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#Single-Cell Analysis

Showing: 45 courses
Broad Institute

Beyond Cells: The Importance of Gene Programs and Tissue Context

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Explore gene programs and tissue context beyond individual cells, uncovering novel insights into pressing biomedical questions through advanced machine learning techniques.
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1 Lesons
1 hour 7 minutes
On-Demand
Free-Video
Broad Institute

Generative AI for Modeling Single-Cell Responses

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Explore generative AI applications in single-cell response modeling, covering data integration, representation learning, and multiomics analysis for biomedical insights.
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23 Lesons
1 hour 2 minutes
On-Demand
Free-Video
Broad Institute

Spatial and Single Cell Diversity of Cells and Humans

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Explore spatial and single-cell diversity in humans, examining how our surroundings influence cellular and individual variations through cutting-edge genomic research.
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1 Lesons
1 hour 18 minutes
On-Demand
Free-Video
Broad Institute

Stochasticity in Transcription - MPG Primer 2023

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Dive into stochasticity in transcription, exploring single-cell data, dynamic regulatory elements, and transcriptional bursting in autoimmune diseases. Gain insights into modeling techniques and gene regulatory programs.
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10 Lesons
50 minutes
On-Demand
Free-Video
Broad Institute

High-Throughput In Silico Genetic Screen for 3D Genome Organization - Models, Inference and Algorithms

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Explore cutting-edge approaches in 3D genome organization research, including in silico genetic screening and graph representation learning for analyzing multiscale chromatin structure.
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2 Lesons
1 hour 50 minutes
On-Demand
Free-Video
The Julia Programming Language

Julia for Biologists - A Perspective on Speed, Abstraction, and Metaprogramming

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Explore Julia's potential in biology: speed, abstraction, and metaprogramming for data analysis, modeling, and research. Learn practical examples and discover the Julia ecosystem for biologists.
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21 Lesons
38 minutes
On-Demand
Free-Video
Labroots

Systematic Characterization of Gene Regulatory Networks Rewiring Patterns Mediated by Non-Coding Regions

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Explore gene regulatory network rewiring patterns through innovative experimental methods and computational approaches for characterizing effects of perturbations at single-cell level.
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12 Lesons
19 minutes
On-Demand
Free-Video
Labroots

Supporting Biomarker Discovery One Cell at a Time - Single Cell Analysis Solutions That Drive Results

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Explore single-cell gene expression analysis for revealing complex cell populations, uncovering regulatory relationships, and visualizing gene expression differences across cell types.
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1 Lesons
25 minutes
On-Demand
Free-Video
Applied Algebraic Topology Network

Cohomology Classes in the RNA Transcriptome

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Explore how cohomology classes in single-cell sequencing data can model transient biological processes, using persistent cohomology and differential forms to infer gene expression dynamics.
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1 Lesons
45 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Inferring Cell-state Dynamics from High-resolution Lineage Tracking of Single Cells

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Explore cell-state dynamics through high-resolution lineage tracking, uncovering insights into cancer progression and potential treatment approaches in this theoretical biology lecture.
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1 Lesons
1 hour 34 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

To Live or Not to Live - Decision Making in Single Cancer Cells - Lecture 1

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Explore decision-making processes in individual cancer cells, examining factors influencing cell survival and death. Gain insights into cellular behavior and its implications for cancer progression and treatment.
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1 Lesons
1 hour 7 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Chance and Necessity: Decision Making in Single Cancer Cells - Lecture 2

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Explore decision-making processes in individual cancer cells, examining the interplay between randomness and determinism in cellular behavior and its implications for cancer progression.
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1 Lesons
1 hour 15 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes

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Explore chromatin architecture from nucleosomes to chromosomes, unraveling its complex organization and role in gene regulation through interdisciplinary perspectives and cutting-edge research.
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1 Lesons
1 hour 4 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Inference from Single Cell Lineage Tracing Data Generated via Genome Editing

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Explore single-cell lineage tracing via genome editing, covering inference methods, design parameters, and data analysis for understanding cellular phylodynamics and evolution.
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21 Lesons
39 minutes
On-Demand
Free-Video
Labroots

Direct cDNA Synthesis Using Template Switching RT for Highly Sensitive Gene Expression Analysis

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Explore reverse transcriptases, template switching RT, and direct cDNA synthesis from cell lysates for enhanced single-cell analysis and gene expression studies.
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1 Lesons
35 minutes
On-Demand
Free-Video
Labroots

Harnessing the Power of Beacon Platform to Accelerate Antibody Discovery and Cell Therapy Development

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Explore Bruker's Beacon® Optofluidic System for comprehensive single-cell analysis, enabling serial multi-modal examination and real-time imaging to accelerate antibody discovery and cell therapy development.
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1 Lesons
23 minutes
On-Demand
Free-Video
Labroots

Cell Pathology Revealed by Single-Cell Genotype-Phenotype Mapping

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Explore single-cell genotype-phenotype mapping to uncover cancer mutation effects and HIV latency mechanisms. Gain insights into tumor heterogeneity and disease progression using advanced genomic methods.
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32 Lesons
33 minutes
On-Demand
Free-Video
Labroots

Single Cell Antibody Discovery Using Islands of Automation

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Explore advanced automation techniques for single cell antibody discovery, focusing on Eli Lilly's 'Islands of Automation' approach to accelerate drug development timelines and increase research efficiency.
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1 Lesons
1 hour 1 minute
On-Demand
Free-Video
International Centre for Theoretical Sciences

Chromatin Readers as Molecular Architects in Shaping Metabolic Landscape

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Explore chromatin 'readers' as molecular architects shaping metabolic landscapes. Delve into interdisciplinary aspects of chromatin organization and gene regulation in this comprehensive lecture.
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1 Lesons
1 hour 56 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Unravelling the Cell-type Specific Roles of Disease-associated Mutations in Chromatin Organization and Gene Regulation

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Explore cell-type specific impacts of disease-associated mutations on chromatin organization and gene regulation through interdisciplinary approaches and cutting-edge techniques.
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1 Lesons
24 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Understanding Epigenetic Mechanisms Through the Engineering of Synthetic Chromatin

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Explore epigenetic mechanisms through synthetic chromatin engineering. Gain insights into chromatin organization and gene regulation using interdisciplinary approaches and cutting-edge techniques.
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1 Lesons
30 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Chromatin 'Readers' as Molecular Architects in Shaping Metabolic Landscape

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Explore chromatin 'readers' as molecular architects shaping metabolic landscapes, delving into interdisciplinary aspects of chromatin organization and gene regulation.
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1 Lesons
24 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

AI-based Chromatin Imaging Biomarkers in Health and Disease

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Explore AI-based chromatin imaging biomarkers and their applications in health and disease. Gain insights into cutting-edge techniques for analyzing chromatin organization and gene regulation.
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1 Lesons
37 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Genome Organization and Regulation: Chromatin Domains, Boundaries and Epigenetics

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Explore chromatin organization and gene regulation through advanced genomics, microscopy, and single-cell measurements. Gain insights into 4D genetic code arrangement and epigenetic influences on gene expression.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Super-silencer Perturbation by EZH2 and REST Inhibition Leads to Large Loss of Gene Repression

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Explore chromatin organization and gene regulation through EZH2 and REST inhibition, focusing on super-silencer perturbation and its significant impacts.
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1 Lesons
16 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

H3S10p Preserves Interphase Memory by Compaction of Active Chromatin in Mitosis

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Explore how H3S10p compacts active chromatin during mitosis, preserving interphase memory. Gain insights into chromatin organization and gene regulation mechanisms.
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1 Lesons
16 minutes
On-Demand
Free-Video
Cancer Genomics Consortium

Deconvoluting the Heterogeneous Signatures of B-cell Acute Lymphoblastic Leukemia

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Explore genomic signatures of B-cell acute lymphoblastic leukemia subtypes and their impact on classification, diagnosis, and treatment strategies for improved patient outcomes.
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1 Lesons
1 hour 2 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Towards an Understanding of Chromatin Remodeler Function in Development at Single-Cell Resolution

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Explore chromatin regulators' role in mammalian development and human disorders through single-cell analysis of mouse knockouts, uncovering developmental impacts and gene networks.
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1 Lesons
52 minutes
On-Demand
Free-Video
Labroots

Picodroplets Enabling High Throughput Single Cell Screening and Isolation

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Explore high-throughput single cell screening and isolation techniques using picodroplets. Learn about innovative technologies advancing cellular biology research and disease mechanism understanding.
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1 Lesons
30 minutes
On-Demand
Free-Video
Labroots

Novel Bioassays in Picodroplets for Single-Cell Analysis

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Explore microfluidic devices for high-throughput bioassays using picodroplets as miniaturized test tubes, revolutionizing drug discovery and preclinical development with efficient single-cell analysis techniques.
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1 Lesons
21 minutes
On-Demand
Free-Video
Labroots

Node-Pore-Sensing: A Versatile Method to Phenotype Cells

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Explore Node-Pore Sensing, an innovative electronic method for cell phenotyping. Learn how this technique measures cell properties and distinguishes sublineages in human mammary epithelial cells.
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1 Lesons
32 minutes
On-Demand
Free-Video
Labroots

Linking Single-Cell Function to Multi-omic Analysis Using 'Lab on a Particle' Technology

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Explore innovative 'Lab on a Particle' technology for single-cell analysis, linking cell function to multi-omic data. Learn about hydrogel microparticles for cell capture and secretion analysis in various applications.
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1 Lesons
43 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Dissecting the Gene Regulatory Grammar at a Single Cell Resolution

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Explore gene regulatory mechanisms at single-cell resolution. Discover cutting-edge techniques for analyzing multimodal data and constructing regulatory networks in genomics research.
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1 Lesons
30 minutes
On-Demand
Free-Video
Valence Labs

Meta Flow Matching - Integrating Vector Fields on the Wasserstein Manifold

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Explore advanced flow-based modeling techniques for predicting biological system dynamics, focusing on population-level evolution and personalized medicine applications using Graph Neural Networks.
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1 Lesons
1 hour 17 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Machine Learning for Single-Cell 3D Epigenomics

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Explore machine learning techniques for analyzing single-cell 3D epigenomics, focusing on genome structure and integrative Hi-C analysis methods for advanced biomedical research.
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1 Lesons
53 minutes
On-Demand
Free-Video
Valence Labs

Contextual AI Models for Single-cell Protein Biology

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Explore PINNACLE, a geometric deep learning approach generating context-aware protein representations for enhanced understanding of protein function and interactions across biological contexts.
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7 Lesons
32 minutes
On-Demand
Free-Video
Labroots

Introducing REM-I: Deepcell's AI-Powered Instrument for Single Cell High-Dimensional Morphology Analysis

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Explore AI-powered single-cell morphology analysis with REM-I, combining high-resolution imaging and deep learning for comprehensive cellular insights.
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1 Lesons
42 minutes
On-Demand
Free-Video
Fields Institute

How to Generate New Hypotheses and Research Directions by Single-Cell Data Analysis

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Discover advanced techniques for analyzing single-cell data to develop innovative research hypotheses and explore new directions in cancer research and mathematical oncology.
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1 Lesons
24 minutes
On-Demand
Free-Video
NASA Astrobiology

Microbial Metabolism in Acidic Brines of Western Australia

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Explore microbial metabolism in acidic brines of Western Australia, examining water activity limits, single-cell analysis, and implications for astrobiology and Mars analogs.
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17 Lesons
17 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Spatial Modeling of Single-Cell Data Using Deep Learning

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Explore deep learning approaches for spatial modeling of single-cell data, focusing on Hi-C reads imputation and transcriptomic data prediction through graph-based methodologies.
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1 Lesons
30 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Alignment, Integration, and Modeling of Spatial Transcriptomics Data

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Explore alignment, integration, and modeling techniques for spatial transcriptomics data, focusing on innovative approaches to analyze gene expression patterns in tissue samples.
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1 Lesons
43 minutes
On-Demand
Free-Video
PoreLab

Microbial Behavior in Porous Media: Hydrodynamics Control on Bacterial Chemotaxis and Biofilm Morphogenesis

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Explore microbial behavior in porous media, focusing on bacterial chemotaxis and biofilm formation. Discover how fluid flow and chemical landscapes impact microbial life and applications in bioremediation and biomineralization.
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1 Lesons
53 minutes
On-Demand
Free-Video
Applied Algebraic Topology Network

Single-cell Trajectory Analysis with V-Mapper

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Explore V-Mapper, an innovative method for analyzing single-cell gene expression data. Learn how it extracts topology and flow of cell differentiation, enhancing trajectory inference in high-dimensional spaces.
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1 Lesons
43 minutes
On-Demand
Free-Video
Broad Institute

Single-Cell Analysis in the Age of Large Language Models

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Explore how biological systems communicate like language, focusing on LLM applications in single-cell analysis, cytokine interactions, and cellular behavior prediction through innovative computational approaches.
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1 Lesons
1 hour 43 minutes
On-Demand
Free-Video
MITCBMM

Identifying Subgroups in Biomedical Datasets Using Data Attribution

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Explore data attribution methods for machine learning models, focusing on identifying disease subtypes and meaningful patterns in biomedical datasets through hands-on practice with datamodels.
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1 Lesons
1 hour 18 minutes
On-Demand
Free-Video