Explore the fascinating 350-year relationship between Mathematics and Physics in this Oxford Mathematics Public Lecture. Delve into the historical interplay between these disciplines, from Newton's Principia to Einstein's struggles and Dirac's mathematical beauty. Examine the contributions of James Clark Maxwell, the French Newton, and the concept of string theory. Investigate the "doubly unreasonable effectiveness" of mathematics in describing the universe and contemplate the future of this intellectual romance. Gain insights into the intersection of these fields and their potential for steady collaboration moving forward.