Explore the landscape of general-purpose frameworks for secure multi-party computation (MPC) in this comprehensive IEEE conference talk. Delve into the capabilities and limitations of eleven cutting-edge MPC systems, including EMP-toolkit, Obliv-C, ObliVM, and SCALE-MAMBA. Gain insights into language expressibility, cryptographic back-ends, and developer accessibility for each framework. Learn about the challenges of implementing MPC and the importance of improved documentation and standardization in the field. Discover recommendations for future compiler development and access virtual environments with pre-installed dependencies for hands-on experimentation with these powerful tools.