Explore an in-depth lecture on minimum spanning tree (MST) interdiction, a complex network optimization problem. Delve into the mathematical foundations and practical applications of interdiction in various contexts, including infection control and infrastructure protection. Learn about the breakthrough O(1)-approximation algorithm that significantly improves upon previous approaches. Examine key concepts such as connectivity interdiction, network interdiction, and mathematical programming techniques. Gain insights into the relationship between MST interdiction and classical graph disconnection problems like the k-cut problem. Follow the high-level approach to solving the maximum component problem and understand the theorem behind the parametric front method. Suitable for those with a strong background in combinatorial optimization and graph theory.