Explore IBM's pioneering role in shaping the science of information in this 57-minute lecture by Dr. John E Kelly, Senior Vice President and Director of IBM Research. Discover why this emerging field is crucial for 21st-century leaders and examine the ongoing transformation in technology. Gain insights into future technological advancements that will revolutionize the world in the coming decade. Learn about IBM's innovative projects in smarter natural resource management, disaster management, and computational life sciences. Delve into key topics such as information technology, systems of systems, DNA transistors, large-scale computing, neural networks, healthcare data, cognitive systems, and the biology of computing. Understand the complexities of technological advancement and scientific discovery while exploring the intersection of soft and firm data, as well as the challenges of distinguishing noise from signal in the information age.