Explore opioid addiction and its treatment options in this comprehensive UCLA lecture by Dr. Belis Aladag. Gain insights into the evolving concept of addiction, focusing on opioid dependence and withdrawal. Examine the prevalence and deadly nature of opioid addiction as a public health crisis. Delve into various treatment modalities, with particular emphasis on methadone maintenance and buprenorphine therapy. Learn about the history of methadone, its administration in clinics, and its effectiveness in reducing overdose fatalities. Compare methadone with buprenorphine (Suboxone, Subutex), understanding their mechanisms of action and treatment retention rates. Discover the cost implications of different treatments and access valuable resources for further information on this critical health issue.