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1
Intro
2
Outline
3
Burden of malaria
4
Malaria life cycle
5
Heterogeneity in malaria prevalence
6
Within-host malaria dynamics
7
Antigenic variation in a single infection
8
Properties of antigenically varying proteins
9
Modeling the human immune response
10
Modeling within-host dynamics
11
Role of immunity
12
Heterogeneities in the model
13
Role of heterogeneities
14
Drivers of within-host dynamics
15
Human-mosquito transmission model
16
Tracking the population immunity
17
PDE model with immunity feedback
18
Response of immunity profiles to change
19
MRC: Dynamics of Infectious Disease
20
Malaria parasite diversity
21
Multi-scale framework
22
Multi-scale model
23
Parasite population richness
24
Parasite population diversity
25
Summary
26
Acknowledgements
27
Thank you!
Description:
Explore the complexities of malaria immunity modeling in this 29-minute lecture from the Workshop on Modelling Immunity. Delve into the burden of malaria, its life cycle, and heterogeneity in prevalence. Examine within-host dynamics, antigenic variation, and the properties of antigenically varying proteins. Learn about modeling human immune responses and within-host dynamics, focusing on the role of immunity and heterogeneities. Investigate human-mosquito transmission models, tracking population immunity, and PDE models with immunity feedback. Discover the dynamics of infectious diseases, malaria parasite diversity, and multi-scale frameworks. Gain insights into parasite population richness and diversity through this comprehensive overview of current research in malaria immunity modeling.

Modelling Immunity to Malaria

Fields Institute
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