Explore mathematical and statistical modeling techniques used in the fight against tuberculosis in this comprehensive lecture. Delve into the history, background, and current challenges of TB control. Examine various modeling approaches, including basic models, latency considerations, and mortality factors. Analyze simulations challenging traditional TB dogma and investigate disease endemic equilibrium scenarios. Learn about context-specific simulations for the Asia Pacific region and toy models. Gain insights into the application of mathematical and statistical methods in understanding and combating tuberculosis, with a focus on integrating experimental and clinical data to inform disease control strategies.