Explore the ethical implications of big tech, research practices, and human rights in this thought-provoking plenary lecture from the 2021 AAAS Annual Meeting. Delve into Mary L. Gray's insights as she examines the intersection of technology, ethics, and society. Gain a deeper understanding of the challenges posed by artificial intelligence and platform economies, drawing from Gray's extensive research on digital labor and the impact of technology on marginalized communities. Learn about the controversial Facebook Contagion Study and its implications for research ethics. Discover key lessons and recommendations for holding computer science and engineering accountable in the digital age. Reflect on the concept of mutuality in research practices and its importance in addressing ethical concerns. Engage with critical questions about the responsibility of tech companies and researchers in safeguarding human rights and dignity in an increasingly digital world.