Explore effective memory management techniques for large-scale JavaScript applications in this JSConf EU 2013 conference talk. Dive into the challenges of memory leaks, frequent garbage collection pauses, and memory bloat in long-running web apps like Gmail. Learn best practices for optimizing memory usage and master the Chrome DevTools Heap Profiler to enhance site performance. Discover how to go beyond automatic garbage collection and implement robust memory management strategies. The presentation covers core concepts, leak characteristics, tools, techniques, and includes a practical demonstration. Note: Audio quality improves after 2:40.