Explore a 16-minute conference talk from the Models of Consciousness Conferences that delves into the concept of physical closure and its implications for quantum collapse theories and consciousness studies. Examine a precise definition of physical closure and its potential impact on physics if the current physical realm is not closed. Investigate the connection between these ideas and scientific theories of consciousness, drawing from recent collaborative research. Follow the speaker's journey through key concepts such as epistemic asymmetry, quantum states, stochastic processes, and dynamical collapse models, culminating in a thought-provoking conclusion about the nature of reality and consciousness.