Explore the future of information technology systems in a post-silicon world through this keynote address. Delve into the challenges and opportunities arising from the slowing of Moore's Law and the emergence of new system architectures. Examine how accelerative elements like FPGAs, GPUs, and synaptic processors are compensating for the limitations of traditional semiconductor advancements. Discover the implications of these changes for information security, including deep encryption and real-time data analytics. Investigate the rise of artificial intelligence and its potential impacts on the industry. Gain insights into the key technological shifts shaping the future of IT, the accelerated pace of innovation, and the associated risks and possibilities in this rapidly evolving landscape.