Explore recent developments in ICM, including GPU acceleration and its applications, in this 25-minute talk by Eugene Raush, Principal Scientist at MolSoft. Delve into topics such as the Rapid Isostere Discovery Engine (RIDE), Atomic Property Fields (APF), and the Rapid Docking GPU Engine (RIDGE). Learn about Molsoft's tools for AI and Deep Learning, including ICM scripting interface for building Deep Learning Networks and comparisons between Graph Convolutional and Fingerprint Based Networks. Discover the implementation and performance of GigaScreen, as well as chemical protonation equilibrium techniques. Gain valuable insights into cutting-edge molecular modeling and drug discovery technologies presented at MolSoft's User Group Meeting.