Dive deep into the Raspberry Pi Pico and RP2040 microcontroller in this comprehensive first class of the HackadayU course. Explore Pi Pico simulation using Wokwi, learn to utilize Serial1 for debug prints, and gain insights into bit manipulation. Examine the RP2040 datasheet, understand the memory space map, and delve into the bus fabric architecture. Master GPIO software control through SIO registers, investigate the GPIO input register, and discover various IO pin functions. Study pad registers and atomic register access, get acquainted with the Pi Pico's C/C++ SDK, and conclude with a bonus demonstration of UART registers. Enhance your microcontroller programming skills and hardware understanding through hands-on examples and in-depth explanations.