Explore the transformative impact of artificial intelligence on scientific research in this 25-minute AAAS Annual Meeting talk. Delve into the deep learning revolution and its applications across various scientific disciplines. Discover how national laboratories and the IT industry are leveraging AI technologies to advance scientific machine learning. Examine specific case studies, including the use of AI in cryoelectron microscopy and the groundbreaking AlphaFold project. Learn about the challenges of adversarial noise in experiments and how AI is being used to overcome these obstacles. Gain insights into the future of AI-driven scientific discovery and its potential to accelerate breakthroughs across multiple fields.