Explore groundbreaking cancer research in this 16-minute TED-Ed talk by Mina Bissell. Discover how the revolutionary idea that cancer cells rely on their microenvironment for tumor development challenges long-held beliefs. Learn about two pivotal experiments that disproved prevailing wisdom on cancer growth. Delve into topics such as developmental biology, the RSV tumor in chickens, embryonic tumor resistance, mammary gland structure, and the role of extracellular matrix in distinguishing normal and malignant cells. Gain insights into the Bissell Laboratory's innovative approach to understanding cancer progression and potential new avenues for treatment.