Explore the epigenetic mechanisms underlying non-small cell lung cancer metastasis to the brain in this 15-minute conference talk from the 2022 Cancer Genomics Consortium Annual Meeting. Delve into Jennifer Karlow's CGC Trainee Award-winning research on the reprogramming of brain development pathways during the metastatic process. Gain insights into the latest findings in cancer genomics and their potential implications for accurate diagnosis and targeted therapies for lung cancer patients with brain metastases.