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1
Introduction
2
Who we are
3
Applications
4
Neutron Transport Equation
5
Disease Model
6
Brain Model
7
Elementary Applications
8
VarianceBased Analysis
9
Multiindex Notation
10
What Went Wrong
11
How Do We Address This
12
Motivation
13
Intuition
14
History
15
Derivative Approximations
16
Questions
17
Limitations
18
Verification
19
Reference
20
Adaptive Step Size
21
Active Subspaces
22
Monte Carlo Sampling
23
Nuclear Example
24
Nuclear Example Results
25
Bayesian Inference
26
Bayesian Inference Example
27
Activity Scores
28
Active Subspace
29
Conclusions
Description:
Explore techniques for isolating influential parameters in engineering and biological models through this comprehensive webinar. Learn about global sensitivity analysis, parameter subset selection, and active subspace techniques as alternatives for identifying key inputs. Discover how Bayesian calibration on active subspaces can quantify uncertainties in physical parameters. Examine real-world applications in nuclear power plant design, quantitative systems pharmacology, and transductive materials. Gain insights from Distinguished University Professor Ralph C. Smith as he shares his expertise in mathematical modeling of smart material systems, numerical analysis, and uncertainty quantification for physical and biological systems.

Parameter Subset Selection and Active Subspace Techniques for Engineering and Biological Models

Inside Livermore Lab
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