Explore a thought-provoking keynote talk where physicist David Sloan advocates for curiosity-driven scientific inquiry and the importance of asking transformative questions about our universe. Delve into how pursuing ambitious, boundary-pushing inquiries can revolutionize our understanding of fundamental concepts like time, consciousness, and reality. Learn about FQxI's mission as the leading organization funding high-risk, high-reward research in foundational science, and discover their expanded initiative to support revolutionary scientific endeavors worldwide. Through this 11-minute presentation, gain insights into how asking profound questions, rather than seeking definitive answers, can lead to paradigm shifts and deeper scientific truths.