Explore the power of F# and Fable in conquering the JavaScript ecosystem in this comprehensive conference talk. Dive into the world of Fable, an open-source compiler that brings F#'s functional paradigm, static typing, and advanced features to JavaScript development. Learn how Fable generates clean ES6-compliant code without runtime overhead, enabling compatibility with modern development tools like Github Electron and React Native. Discover real-world applications of Fable, including cross-platform desktop and mobile app development. Gain insights into Fable's newest features, its growing community, and the vast opportunities it presents for F# developers. From practical demos to production examples, this talk covers everything from basic concepts to advanced techniques, including async operations, browser APIs, and seamless JavaScript interaction.