Explore the groundbreaking CAR T-cell therapy for pediatric cancer patients in this informative lecture by UCLA pediatric oncologist Dr. Satiro De Oliveira. Gain insights into the fundamentals of cellular therapy, the mechanics of Chimeric Antigen Receptors (CARs), and their revolutionary impact on cancer treatment. Discover the specific indications for CAR T-cell therapy, the manufacturing process, and FDA-approved products. Learn about remission rates, potential side effects including cytokine release syndrome and neurological toxicities, and essential safety precautions. Understand the key takeaway messages that highlight the significance of this innovative approach in pediatric oncology. This comprehensive overview provides valuable information for healthcare professionals, patients, and families navigating the complexities of childhood cancer treatment.