Explore the cutting-edge research on understanding the neocortex through a comprehensive lecture that delves into big science, team science, and open science approaches. Discover the complexities of the human brain, including its connectome, physical tissue, and evolution. Learn about various cell types, neuroscience advancements, and the challenges faced in brain research. Examine the funding, milestones, and infrastructure supporting this groundbreaking work, including the development of new facilities and open data initiatives. Investigate innovative projects such as the Mine Scope and Pipeline Project, focusing on the visual system and whole brain data analysis. Gain insights into in vitro single cell characterization, transcriptomics, and the creation of a periodic table for cell types. Conclude with an exploration of the Brain Observatory and its applications in micromechanics and intrinsic imaging, providing a comprehensive overview of the latest advancements in neocortex research. Read more