Explore the historical background and fundamental mechanisms of bacterial antibiotic resistance in this 23-minute lecture by Dr. Marilyn Roberts from the University of Washington. Delve into the basic elements of bacterial antibiotic resistance gene transfer, including plasmids, transposons, and integrons. Learn about the legacy of antibiotics, their targets, and the various types of resistance mechanisms employed by bacteria. Understand the importance of resistant bacteria and the spread of antibiotic-resistant genes, including their presence in food microbes. Gain insights into the ongoing battle between bacteria and human efforts to combat infections through this comprehensive overview presented by a fellow of the American Academy of Microbiology.