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DATE: 09 December 2019, 16:00 to
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Lecture 1: 9 December 2019, PM
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Lecture 2: 10 December 2019, PM
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Lecture 3: 11 December 2019, PM
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Lecture 4: 12 December 2019, PM
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Active processes in cells and tissues Lecture 1
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Welcome to ICTS-TIFR
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Established in 2007 by the TIFR Campus Imagined in 2007
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Programs
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Infrastructure at ICTS
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ICTS Research
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ICTS Faculty
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ICTS Programs
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What distinguishes ICTS Programs?
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ICTS Programs-Format and Duration
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Organisational Features
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Impact of ICTS Programs
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ICTS Programs - A National Resource
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Gender Balance in ICTS Programs
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ICTS Programs - Special Lectures
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ICTS Outreach Initiatives
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ICTS at Ten - The 10th Year Celebration
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Thank you! See you again at ICTS!
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Active Processes in Cells and Tissues
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Lecture I Symmetry breaking of biological cells
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Lecture I - Outline
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Cell movements
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Molecular motors
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Motility assay
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Active filament networks
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Passive and active systems
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Cell division
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From a single cell to an organism
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Cell polarity and cell chirality
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Asymmetric cell division
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Cell polarity
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Cell polarity and flows
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Mechano-chemical patterning
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The cell cortex
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Active fluids
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Force dipoles
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Active stress
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Cell surface tension
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Rheology of the cell cortex
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Constitutive equation
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Thin active film
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Step change of active tension
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Hydrodynamic length scale
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Flow measurements
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Active stress and flow profile
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Self-organisation of active fluids
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Dynamic pattern - steady state
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Geometry of surfaces
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Constitutive equations
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Mechano-chemical instability on a sphere
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Establishment of cell polarity
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A mechano-chemical switch
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Quantification and comparison
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Spontaneous flow instability
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Stability diagram
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Spontaneous formation of a contractile ring
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Self-organization of shape
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Force and torque balances
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Instability of an active sphere
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Shape instabilities
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Tubular instability
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Chirality
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Chiral flow patterns
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Enhanced chiral flows
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Active chiral processes
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Thin chiral active gel
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Active stress and chiral flows
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Chiral flows
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Left-right symmetry breaking in the roundworm
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Rotation of cell division axis
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Chiral velocity
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Symmetric division: chiral flows
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Chiral flows rotate division axis
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Left-right asymmetry of organisms
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Left-right asymmetry in mammals
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Chirality in Biology
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Symmetry breaking by active processes
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Mechano-chemical instabilities of active surfaces
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Max Planck Institute for the Physics of Complex Systems
Description:
Explore the fascinating world of active processes in cells and tissues in this lecture by Frank Jülicher from the Max Planck Institute for the Physics of Complex Systems. Delve into the dynamic nature of living matter and how it organizes into complex patterns and spatial structures. Examine fundamental biological questions about the emergence of spatial patterns and morphologies at cellular and multicellular scales. Discover how living systems are driven far from thermodynamic equilibrium by constant energy flux through metabolic processes. Investigate key concepts such as cell symmetry breaking, polarity, and chirality, and their roles in organism development. Learn about fluid flows generated by active processes and their importance in cellular symmetry breaking. Explore collective organization during morphogenesis, including tissue remodeling through cell rearrangements, divisions, and flows. Gain insights into how cells and tissues behave as a form of active matter with unique dynamics and material properties crucial for biological morphogenesis. Read more

Active Processes in Cells and Tissues - Symmetry Breaking of Biological Cells - Lecture 1

International Centre for Theoretical Sciences
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