Cell-based SPR Microscopy Application in Drug Discovery

Cell-based SPR Microscopy Application in Drug Discovery

Explore the application of Surface Plasmon Resonance Microscopy (SPRm) in drug discovery through this 55-minute webinar presented by Dr. Shijie Wu and Dr. Marie-Laure Rives. Gain insights into this novel technology that enables label-free, real-time measurements of binding affinity and kinetics between small molecules and G protein-coupled receptors (GPCRs) under physiological conditions. Learn about the limitations of Compound 13, a selective antagonist of GPR4, through pH-dependent binding studies. Discover examples of compound and antibody binding, and understand how SPRm provides more relevant information about binding events in drug discovery processes.