Evolution of Gene Regulation Following Whole Genome Duplication in Salmonids
Explore the evolution of gene regulation following whole genome duplication in salmonids through this comprehensive seminar. Delve into the fascinating world of salmonid genomics, focusing on the Atlantic salmon as a model for genome evolution after whole genome duplication. Examine gene loss and retention patterns, tissue regulatory divergence, and the challenges of distinguishing between evolutionary scenarios. Learn about the Ornstein-Uhlenbeck model as a framework for modeling expression evolution. Investigate expression level shifts, tissue-specific evolution, and ongoing pseudogenization. Discover the role of cis-regulatory elements in duplicate expression evolution through ATAC-seq and TFBS footprinting techniques. Gain insights into how transposable elements contribute to novel adaptive expression phenotypes in salmonids. Conclude with a summary of key findings and their implications for understanding genome evolution in these economically and culturally significant fish species. Read more