Bone Marrow Transplant in Sickle Cell Disease

Bone Marrow Transplant in Sickle Cell Disease

Explore the indications, techniques, and complications of bone marrow transplantation in sickle cell disease in this 45-minute lecture. Delve into the pathophysiology, donor selection process, and various stem cell sources. Learn about conditioning agents, pre-transplant discussions, and the ideal regimen for BMT in SCD. Examine common complications such as graft-versus-host disease, posterior reversible encephalopathy syndrome, sinusoidal obstruction syndrome, and transplant-associated microangiopathy. Gain insights into the challenges faced during BMT for sickle cell patients and understand the current treatment approaches.