Current and Evolving Understanding in Hypertrophic Cardiomyopathy - Cardiology Grand Rounds
Explore the latest developments in hypertrophic cardiomyopathy (HCM) through this comprehensive cardiology grand rounds lecture. Delve into multimodality imaging techniques for accurate HCM diagnosis, including recognition of apical aneurysms and LV strain analysis. Learn about the NIH-sponsored HCMR Registry and the application of machine learning and AI in HCM research. Understand the importance of eliciting left ventricular outflow tract (LVOT) obstruction and recognizing typical and atypical variants of obstructive HCM. Examine sudden cardiac death risk stratification, comparing ESC and American approaches to ICD placement. Discover management strategies for obstructive HCM, including lifestyle considerations and the LIVE-HCM Trial on vigorous exercise. Explore septal reduction therapies, including surgical approaches and alcohol septal ablation. Gain insights into new pharmacological treatments, such as Mavacamten, and their impact on disease phenotype and cardiac remodeling. Discuss gene therapy prospects and the management of arrhythmias in HCM patients. Finally, learn about genetic testing, long-term outcomes from the SHARE registry, and screening protocols for asymptomatic first-degree relatives. Read more