MPG Primer: Sequencing and Analysis of Long-Read Whole Genome Data - 2024
Explore long-read whole genome sequencing and analysis techniques, focusing on advanced methods for medical and population genetics research.
Non-Coding Aberrations in Mismatch Repair Genes Underlie a Substantial Part of the Missing Heritability in Lynch Syndrome
Explore non-coding aberrations in mismatch repair genes and their role in Lynch syndrome heritability. Gain insights into diagnostic approaches and functional testing methods.
Low Error Rate Long-Reads Enable the Identification of Long Variant Haplotypes in Metagenome Assemblies
Explore how low error rate long-reads improve metagenome assembly, enabling identification of long variant haplotypes in microbial communities. Learn about overcoming challenges in separating closely related organisms.
Studying Promoter and Isoform Diversity with Long-Read Transcriptome Sequencing
Explore promoter and isoform diversity in cancer transcriptomes using long-read RNA sequencing. Gain insights into alternative promoters' role in gene regulation and their impact on cancer research.
Hands-on Introduction to Pangenome Graphs
Explore pangenome graphs hands-on: learn data structures, applications, and tools for analyzing genomic variations across populations in this practical introduction.
Recent Progress Towards Petabase-Scale Genomics
Explore recent advancements in petabase-scale genomics, focusing on efficient whole-genome assembly techniques and large-scale sequence alignment for viral discovery.
Comprehensive Structural Variant Detection: From Mosaic to Population Level
Explore advanced structural variant detection using Sniffles2, a powerful tool for identifying complex genomic alterations with increased accuracy, speed, and functionality in long-read sequencing data.
A Structural Variation Map of 499 Han Chinese Individuals Using Long-Read Sequencing Data
Explore a comprehensive structural variation map of Han Chinese genomes using long-read sequencing, uncovering genetic insights and implications for human evolution and disease.
Deciphering Brain Mosaicism with Long-read Sequencing
Explore how somatic mutations in brain development contribute to neurodevelopmental disorders using integrated single-cell and long-read RNA sequencing techniques.
Application of Long-read Sequencing in Human Genetics
Explore long-read sequencing's revolutionary impact on human genetics, enabling rapid genome assembly and comprehensive variation detection for enhanced disease understanding.
Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read Sequencing
Explore a novel long-read sequencing method for detecting single-strand DNA mismatches and damage, enabling new insights into mutation origins in healthy tissues and cancer.
Long-read Sequencing at Scale and High Accuracy
Explore long-read sequencing's advantages in genome analysis, focusing on accuracy improvements for complex genes and large-scale cohort studies in personalized medicine initiatives.
Hanging by a Thread: Using High Fidelity Long-Read Sequencing to Uncover the Genomic Basis of Insect Silk
Explore genomic advances in silk research using high fidelity long-read sequencing. Uncover hidden variations in silk genes across insects and spiders, revolutionizing our understanding of this remarkable biomaterial.
A Scalable, Cost-Efficient Method for Targeted Enrichment of Long Fragments for Third-Gen Sequencing
Discover a scalable targeted enrichment protocol for long DNA fragments, demonstrated with a custom blood group panel and highly multiplexed enrichment pool of 16 samples.
Investigating Structural Variants in Cancer Genomics - A Bioinformatics Tutorial
Explore bioinformatics tools Ribbon and SplitThreader to analyze structural variants in cancer genomes using long-read sequencing data and GIAB's HG008 tumor/normal samples.