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#Long Read Sequencing

Showing: 15 courses
Broad Institute

MPG Primer: Sequencing and Analysis of Long-Read Whole Genome Data - 2024

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Explore long-read whole genome sequencing and analysis techniques, focusing on advanced methods for medical and population genetics research.
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1 Lesons
49 minutes
On-Demand
Free-Video
Labroots

Non-Coding Aberrations in Mismatch Repair Genes Underlie a Substantial Part of the Missing Heritability in Lynch Syndrome

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Explore non-coding aberrations in mismatch repair genes and their role in Lynch syndrome heritability. Gain insights into diagnostic approaches and functional testing methods.
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21 Lesons
29 minutes
On-Demand
Free-Video
Labroots

Low Error Rate Long-Reads Enable the Identification of Long Variant Haplotypes in Metagenome Assemblies

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Explore how low error rate long-reads improve metagenome assembly, enabling identification of long variant haplotypes in microbial communities. Learn about overcoming challenges in separating closely related organisms.
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1 Lesons
30 minutes
On-Demand
Free-Video
Labroots

Studying Promoter and Isoform Diversity with Long-Read Transcriptome Sequencing

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Explore promoter and isoform diversity in cancer transcriptomes using long-read RNA sequencing. Gain insights into alternative promoters' role in gene regulation and their impact on cancer research.
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1 Lesons
32 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Hands-on Introduction to Pangenome Graphs

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Explore pangenome graphs hands-on: learn data structures, applications, and tools for analyzing genomic variations across populations in this practical introduction.
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1 Lesons
41 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Recent Progress Towards Petabase-Scale Genomics

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Explore recent advancements in petabase-scale genomics, focusing on efficient whole-genome assembly techniques and large-scale sequence alignment for viral discovery.
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1 Lesons
41 minutes
On-Demand
Free-Video
Labroots

Comprehensive Structural Variant Detection: From Mosaic to Population Level

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Explore advanced structural variant detection using Sniffles2, a powerful tool for identifying complex genomic alterations with increased accuracy, speed, and functionality in long-read sequencing data.
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1 Lesons
26 minutes
On-Demand
Free-Video
Labroots

A Structural Variation Map of 499 Han Chinese Individuals Using Long-Read Sequencing Data

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Explore a comprehensive structural variation map of Han Chinese genomes using long-read sequencing, uncovering genetic insights and implications for human evolution and disease.
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17 Lesons
51 minutes
On-Demand
Free-Video
Labroots

Deciphering Brain Mosaicism with Long-read Sequencing

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Explore how somatic mutations in brain development contribute to neurodevelopmental disorders using integrated single-cell and long-read RNA sequencing techniques.
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20 Lesons
25 minutes
On-Demand
Free-Video
Labroots

Application of Long-read Sequencing in Human Genetics

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Explore long-read sequencing's revolutionary impact on human genetics, enabling rapid genome assembly and comprehensive variation detection for enhanced disease understanding.
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1 Lesons
31 minutes
On-Demand
Free-Video
Labroots

Sequencing Single-Strand Mismatch and Damage Patterns by Long-Read Sequencing

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Explore a novel long-read sequencing method for detecting single-strand DNA mismatches and damage, enabling new insights into mutation origins in healthy tissues and cancer.
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1 Lesons
26 minutes
On-Demand
Free-Video
Labroots

Long-read Sequencing at Scale and High Accuracy

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Explore long-read sequencing's advantages in genome analysis, focusing on accuracy improvements for complex genes and large-scale cohort studies in personalized medicine initiatives.
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1 Lesons
31 minutes
On-Demand
Free-Video
Labroots

Hanging by a Thread: Using High Fidelity Long-Read Sequencing to Uncover the Genomic Basis of Insect Silk

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Explore genomic advances in silk research using high fidelity long-read sequencing. Uncover hidden variations in silk genes across insects and spiders, revolutionizing our understanding of this remarkable biomaterial.
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1 Lesons
31 minutes
On-Demand
Free-Video
Integrated DNA Technologies (IDT)

A Scalable, Cost-Efficient Method for Targeted Enrichment of Long Fragments for Third-Gen Sequencing

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Discover a scalable targeted enrichment protocol for long DNA fragments, demonstrated with a custom blood group panel and highly multiplexed enrichment pool of 16 samples.
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1 Lesons
37 minutes
On-Demand
Free-Video
OMGenomics

Investigating Structural Variants in Cancer Genomics - A Bioinformatics Tutorial

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Explore bioinformatics tools Ribbon and SplitThreader to analyze structural variants in cancer genomes using long-read sequencing data and GIAB's HG008 tumor/normal samples.
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1 Lesons
26 minutes
On-Demand
Free-Video