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#Gene Regulation

Showing: 59 courses
Manolis Kellis

AI in Medicine - Keynote at Cambridge CCAIM24 Summer School

1 rewiews
Explore AI's transformative impact on medicine with insights from a leading expert, covering cutting-edge applications and future possibilities in healthcare.
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1 Lesons
1 hour 10 minutes
On-Demand
Free-Video
Santa Fe Institute

Entangled Adaptive Landscapes Facilitate Exaptation in Gene Regulation

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Explore the evolution of gene regulation through exaptation, focusing on transcription factor binding sites and their adaptive landscapes in E. coli, revealing insights into evolutionary innovations.
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1 Lesons
1 hour 2 minutes
On-Demand
Free-Video
Broad Institute

Biomolecular Condensates: New Insights into Regulation and Dysregulation of Cellular Compartments

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Explore biomolecular condensates and their role in cellular compartment regulation with Professor Richard Young's seminar on cutting-edge chemical biology research.
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1 Lesons
1 hour 7 minutes
On-Demand
Free-Video
Broad Institute

Linking Structure to Function in Metabolic and Blood Disorders Using Region Capture Micro-C

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Explore linking structure to function in metabolic and blood disorders using Region Capture Micro-C, presented by PhD student Viraat Goel at the Broad Institute symposium.
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1 Lesons
34 minutes
On-Demand
Free-Video
Broad Institute

Stochasticity in Transcription - MPG Primer 2023

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Dive into stochasticity in transcription, exploring single-cell data, dynamic regulatory elements, and transcriptional bursting in autoimmune diseases. Gain insights into modeling techniques and gene regulatory programs.
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10 Lesons
50 minutes
On-Demand
Free-Video
Cardiology University of Washington

Regulators of Fibroblast Fate and Fibrosis in Cardiac Response to Myocardial Infarction

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Uncover the role of fibroblasts in cardiac response to myocardial infarction and explore how transcriptome modifications impact heart recovery and fibrosis in acute and chronic stress.
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1 Lesons
40 minutes
On-Demand
Free-Video
EACRvideos

The Impact of RNA Modifications on Normal and Malignant Haematopoiesis

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Explore RNA modifications' influence on normal and malignant blood cell formation with insights from cutting-edge research in stem cell biology and cancer plasticity.
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1 Lesons
26 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Advances in Predictive Models for Single-cell and Regulatory Genomics

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Explore cutting-edge predictive models for single-cell and regulatory genomics, enhancing understanding of cancer progression and potential treatment approaches.
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1 Lesons
1 hour 14 minutes
On-Demand
Free-Video
Labroots

Studying Promoter and Isoform Diversity with Long-Read Transcriptome Sequencing

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Explore promoter and isoform diversity in cancer transcriptomes using long-read RNA sequencing. Gain insights into alternative promoters' role in gene regulation and their impact on cancer research.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Coarse-grained Simulations of Nucleosomes

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Explore coarse-grained simulations of nucleosomes to understand chromatin organization and gene regulation through interdisciplinary computational modeling techniques.
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1 Lesons
17 minutes
On-Demand
Free-Video
Alan Turing Institute

From Causal Inference to Autoencoders, Memorization & Gene Regulation - Caroline Uhler, MIT

0 rewiews
Exploring causal inference, autoencoders, and gene regulation through genomics and 3D genome organization. Integrates data modalities, analyzes overparameterized autoencoders, and links memorization to real-valued data retrieval.
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16 Lesons
42 minutes
On-Demand
Free-Video
Fields Institute

Modelling the Erosion of Epigenetic Landscapes in Cancer and Ageing

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Explore mathematical models of epigenetic landscapes in cancer and aging, focusing on erosion processes and their implications for disease progression and cellular behavior.
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8 Lesons
21 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Quantifying the Physical Genome - Understanding Regulatory Elements and Transcription Factor Dynamics

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Delve into groundbreaking research on genome regulation, exploring how transcription factors and regulatory elements control gene expression and cellular diversity in human development through advanced sequencing methods.
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1 Lesons
1 hour 18 minutes
On-Demand
Free-Video
The Royal Institution

What Is Life? - With Paul Nurse

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Nobel laureate Paul Nurse explores the fundamental question of defining life, examining key biological principles and their broader implications for understanding living organisms and their evolution.
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14 Lesons
1 hour
On-Demand
Free-Video
Medicosis Perfectionalis

Lac Operon and Trp Operon - Regulator, Promotor, Operator - A Comprehensive Explanation from A to Z

0 rewiews
Comprehensive explanation of Lac and Trp operons, covering gene expression control in prokaryotes. Explores regulatory mechanisms, structural components, and metabolic adaptations in bacteria.
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8 Lesons
21 minutes
On-Demand
Free-Video
EvoEcoSeminars

Caroline Dean - Adapting to Different Winters: Non-Coding Transcripts and Epigenetic Switches at FLC

0 rewiews
Explore plant adaptation to winter through FLC regulation, epigenetic switches, and non-coding transcripts. Discover temperature sensing and natural variation in vernalization across populations.
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28 Lesons
1 hour 2 minutes
On-Demand
Free-Video
EvoEcoSeminars

Wings, Feathers, Flight - The PhyloG2P Approach to Understanding Bird Biology

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Explore bird biology through phylogenetics, focusing on genotype-phenotype connections, regulatory evolution, and flightlessness. Gain insights into feather origins and avian adaptations.
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33 Lesons
1 hour 1 minute
On-Demand
Free-Video
EvoEcoSeminars

Evolution of Gene Regulation Following Whole Genome Duplication in Salmonids

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Explore gene regulation evolution in salmonids post-genome duplication. Discover tissue-specific changes, regulatory divergence, and the impact on expression phenotypes.
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25 Lesons
58 minutes
On-Demand
Free-Video
North Carolina School of Science and Mathematics

Lac Operon Gene Regulation Activity - Visualizing Cis and Trans Elements

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Visualize gene regulation of the lac operon through an interactive activity, exploring cis- and trans-acting elements in single copy and partial diploid scenarios.
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8 Lesons
21 minutes
On-Demand
Free-Video
Society for Experimental Biology

GARP Transcription Factors Repress Arabidopsis - Alaeddine Safi

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Explore how GARP transcription factors regulate Arabidopsis nitrogen starvation response through ROS-dependent and -independent pathways in this insightful botanical research presentation.
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1 Lesons
43 minutes
On-Demand
Free-Video
Society for Experimental Biology

Antagonistic Role of Histone H1 on the H3K27me3 by Clara Richet-Bourbousse

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Explore histone H1's antagonistic role on H3K27me3 repressive landscape over genes and telomeric repeats in this insightful presentation by Clara Richet-Bourbousse.
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1 Lesons
21 minutes
On-Demand
Free-Video
Bioinformagician

Introduction to Motif Discovery and Transcription Factor Binding Site Analysis

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Comprehensive guide to motif discovery and transcription factor binding site analysis, covering basics, tools, and practical demonstrations using Homer software for ChIP-seq data analysis.
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21 Lesons
52 minutes
On-Demand
Free-Video
Simons Institute

Debugging Genomic Profiling Experiments and Predictive Models with Interpretation Tools

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Explore deep learning models in genomics, uncovering latent biases and technical artifacts. Learn to design efficient models that correct biases and reveal novel insights into gene regulation.
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1 Lesons
1 hour 4 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Nuclear Envelope Proteins Regulate Chromosome Territory and Gene Loci Dynamics

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Explore nuclear envelope proteins' role in regulating chromosome territories and gene loci dynamics through an in-depth lecture by Kundan Sengupta.
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1 Lesons
1 hour 27 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Excavating the Architecture of Chromatin: From Nucleosomes to Chromosomes

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Explore chromatin architecture from nucleosomes to chromosomes, unraveling its complex organization and role in gene regulation through interdisciplinary perspectives and cutting-edge research.
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1 Lesons
1 hour 4 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Understanding GWAS Mechanisms with Transcriptome-Wide Association Studies

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Explore GWAS mechanisms through Transcriptome-Wide Association Studies. Learn to identify genetic determinants of chromatin and quantify genetic effects on disease mediated by gene expression levels.
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1 Lesons
41 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

BART: A Transcriptional Regulator Prediction Method for Functional Genomics

0 rewiews
Explore BART, a powerful method for predicting transcriptional regulators in functional genomics. Learn its applications, underlying algorithms, and impact on gene regulation research.
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1 Lesons
32 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Leveraging High-throughput Functional Characterization Data to Dissect and Annotate Human Regulatory Regions

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Explore high-throughput functional characterization techniques for dissecting and annotating human regulatory regions, leveraging advanced genomic mapping and integrative epigenomic approaches.
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1 Lesons
33 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Probing Principles of Genome Organization and Function

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Explore innovative genomics technologies for understanding gene regulation and chromatin organization in mammalian cells. Discover approaches to alter genomic structure and study its impact.
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12 Lesons
54 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Alterations in Spatial Genome Compartmentalization Associated with Constriction and Expansion

0 rewiews
Explore 3D genome structure changes in cells under physical stress, examining constricted migration and nuclear expansion effects on chromosome organization and gene expression.
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1 Lesons
52 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Chromatin Readers as Molecular Architects in Shaping Metabolic Landscape

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Explore chromatin 'readers' as molecular architects shaping metabolic landscapes. Delve into interdisciplinary aspects of chromatin organization and gene regulation in this comprehensive lecture.
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1 Lesons
1 hour 56 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Untangling Enhancer-Promoter Interactions Throughout Mouse Development

0 rewiews
Explore enhancer-promoter interactions in mouse development, unraveling complex gene regulation mechanisms and their impact on chromatin organization.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Decoding Regulatory Diversity Within DNA Regions

0 rewiews
Explore DNA regulatory diversity through advanced genomics, microscopy, and single-cell measurements. Gain insights into chromatin organization and gene regulation principles.
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1 Lesons
33 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Unravelling the Cell-type Specific Roles of Disease-associated Mutations in Chromatin Organization and Gene Regulation

0 rewiews
Explore cell-type specific impacts of disease-associated mutations on chromatin organization and gene regulation through interdisciplinary approaches and cutting-edge techniques.
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1 Lesons
24 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Revealing the Mechanism of Genome Organization Using Single-molecule Approaches

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Explore genome organization mechanisms through single-molecule approaches. Gain insights into chromatin structure and gene regulation using cutting-edge techniques.
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1 Lesons
29 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Understanding Epigenetic Mechanisms Through the Engineering of Synthetic Chromatin

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Explore epigenetic mechanisms through synthetic chromatin engineering. Gain insights into chromatin organization and gene regulation using interdisciplinary approaches and cutting-edge techniques.
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1 Lesons
30 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

The Role of Polymerases in Driving the 4D Genome

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Explore the impact of polymerases on chromatin's 4D organization and gene regulation in this insightful talk by Daniel Jost on cutting-edge genomics research.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Signalling from the Wings: Telomeres Impact Chromatin Genomewide

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Explore how telomeres influence chromatin structure and gene regulation across the entire genome, uncovering their far-reaching impact on cellular processes.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Chromatin 'Readers' as Molecular Architects in Shaping Metabolic Landscape

0 rewiews
Explore chromatin 'readers' as molecular architects shaping metabolic landscapes, delving into interdisciplinary aspects of chromatin organization and gene regulation.
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1 Lesons
24 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

AI-based Chromatin Imaging Biomarkers in Health and Disease

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Explore AI-based chromatin imaging biomarkers and their applications in health and disease. Gain insights into cutting-edge techniques for analyzing chromatin organization and gene regulation.
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1 Lesons
37 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

On the Role of Polymerases in Driving the 4D Genome

0 rewiews
Explore the impact of polymerases on 4D genome organization and gene regulation in this in-depth talk by Daniel Jost, part of a comprehensive chromatin research program.
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1 Lesons
1 hour 10 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Genome Organization and Regulation: Chromatin Domains, Boundaries and Epigenetics

0 rewiews
Explore chromatin organization and gene regulation through advanced genomics, microscopy, and single-cell measurements. Gain insights into 4D genetic code arrangement and epigenetic influences on gene expression.
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1 Lesons
32 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Nanopore Sensing of DNA-Histone Complexes on Nucleosome Arrays

0 rewiews
Explore nanopore sensing techniques for analyzing DNA-histone complexes in nucleosome arrays, advancing understanding of chromatin organization and gene regulation.
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1 Lesons
19 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Protein Search Processes Mediated by Chromatin Topology

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Explore protein search processes influenced by chromatin topology, uncovering mechanisms of gene regulation and DNA-protein interactions in the cellular environment.
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1 Lesons
12 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

Super-silencer Perturbation by EZH2 and REST Inhibition Leads to Large Loss of Gene Repression

0 rewiews
Explore chromatin organization and gene regulation through EZH2 and REST inhibition, focusing on super-silencer perturbation and its significant impacts.
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1 Lesons
16 minutes
On-Demand
Free-Video
International Centre for Theoretical Sciences

H3S10p Preserves Interphase Memory by Compaction of Active Chromatin in Mitosis

0 rewiews
Explore how H3S10p compacts active chromatin during mitosis, preserving interphase memory. Gain insights into chromatin organization and gene regulation mechanisms.
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1 Lesons
16 minutes
On-Demand
Free-Video
Cancer Genomics Consortium

Constitutional DNA Methylation Testing in the Clinical Setting

0 rewiews
Explore DNA methylation testing's clinical applications for diagnosing epigenetic disorders, understanding gene regulation, and enhancing genomic diagnostics.
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1 Lesons
1 hour 5 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Gene Regulation in Cellular Senescence

0 rewiews
Explore gene regulation in cellular senescence with Prof. Masashi Narita, uncovering key insights on epigenetic aspects and senescence-associated heterochromatic foci (SAHFs).
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1 Lesons
35 minutes
On-Demand
Free-Video
Center for Physical Genomics and Engineering

Towards an Understanding of Chromatin Remodeler Function in Development at Single-Cell Resolution

0 rewiews
Explore chromatin regulators' role in mammalian development and human disorders through single-cell analysis of mouse knockouts, uncovering developmental impacts and gene networks.
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1 Lesons
52 minutes
On-Demand
Free-Video
Valence Labs

Designing DNA with Tunable Regulatory Activity Using Discrete Diffusion

0 rewiews
Explore DNA Discrete Diffusion (D3) for engineering regulatory DNA sequences with targeted functional activity levels. Learn about its advantages, evaluation metrics, and applications in functional genomics.
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9 Lesons
1 hour 19 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Computational Methods for Modeling and Analyzing Epigenomic Data

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Explore computational methods for modeling and analyzing epigenomic data, focusing on chromatin state annotation, gene-based modeling, and cross-species conservation in functional genomics.
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1 Lesons
23 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Dissecting the Gene Regulatory Grammar at a Single Cell Resolution

0 rewiews
Explore gene regulatory mechanisms at single-cell resolution. Discover cutting-edge techniques for analyzing multimodal data and constructing regulatory networks in genomics research.
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1 Lesons
30 minutes
On-Demand
Free-Video
Computational Genomics Summer Institute CGSI

Machine Learning Models for Single Cell and Regulatory Genomics - CGSI 2023

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Explore machine learning models for single-cell and regulatory genomics, focusing on recent research and applications in computational biology.
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1 Lesons
48 minutes
On-Demand
Free-Video
Animated biology With arpan

Proto-oncogenes: How They Lead to Cancer - The Biology of Proto-oncogenes

0 rewiews
Explore proto-oncogenes and their role in cancer development. Understand the biology behind these genes and their significance in USMLE preparation.
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1 Lesons
12 minutes
On-Demand
Free-Video
Animated biology With arpan

Transcription Factors, General Transcription Factors, and Transcription Factor Networks in Molecular Biology

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Explore transcription factors, their general types, and complex networks in molecular biology. Gain insights into gene regulation mechanisms and their importance in cellular processes.
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1 Lesons
10 minutes
On-Demand
Free-Video
Johns Hopkins Medicine

miRNA Export, Transport and Uptake via Extracellular Vesicles in Mammalian Cells

0 rewiews
Explore miRNA dynamics in mammalian cells, focusing on export, transport, and uptake through extracellular vesicles. Gain insights from expert Dr. Suvendra Battacharyya.
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1 Lesons
54 minutes
On-Demand
Free-Video
Valence Labs

HyenaDNA: Long-Range Genomic Sequence Modeling at Single Nucleotide Resolution

0 rewiews
Explore HyenaDNA: a genomic foundation model using long-range context and single nucleotide resolution. Learn about its design, experiments, and state-of-the-art performance in genomic sequence modeling.
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6 Lesons
1 hour 21 minutes
On-Demand
Free-Video
Manolis Kellis

Regulatory Circuitry and Networks - Lecture 7

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Explore regulatory circuitry and networks in biological systems, focusing on gene regulation mechanisms and their interconnected pathways.
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1 Lesons
1 hour 20 minutes
On-Demand
Free-Video
Manolis Kellis

Regulatory Circuitry - Lecture 6

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Explore regulatory circuitry in genomics, uncovering mechanisms of gene expression control and cellular regulation through advanced computational analysis techniques.
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1 Lesons
1 hour 23 minutes
On-Demand
Free-Video