Explore a groundbreaking approach to sequence alignment in this 47-minute conference talk from the Computational Genomics Summer Institute (CGSI) 2024. Delve into Pavel Pevzner's presentation on UniAligner, a parameter-free framework designed for fast and accurate sequence alignment. Learn about the innovative techniques that eliminate the need for parameter tuning, potentially revolutionizing genomic analysis. Gain insights into the methodology behind UniAligner and its implications for computational biology, as discussed in the related paper by Andrey Bzikadze and Pavel Pevzner published in Nature Methods, 2023. Discover how this new framework could streamline and enhance the accuracy of sequence alignment processes in genomic research.