Explore the evolving landscape of cardiovascular health in this 1-hour 3-minute grand rounds presentation from the University of Washington's Cardiology department. Delve into the shift from disease treatment to health promotion, focusing on subclinical identification through imaging and genetics. Examine specific data illustrating this evolution and its impact on cardiovascular wellness. Learn about imaging technology advancements, early disease development across different age groups, and the role of guidelines in preventive care. Investigate emerging concepts such as clonal hematopoiesis, TP53 mutations, and their implications for cardiovascular and cognitive health. Gain insights into the intersection of genetics, brain function, and cardiovascular well-being throughout the lifespan.