Explore cross-cohort analysis through cloud genomics in this 46-minute Medical and Population Genetics Primer talk by Margaret Sunitha from MGH and The Broad Institute. Delve into the benefits of cloud computing for genomic research, trusted research environments, and project methodologies. Learn about batch effects, scientific differences in variants, and the complexities of cloud-based genomic analysis. Gain insights into current capabilities, workflow overviews, and cost considerations. The talk includes a demonstration of Jupiter Notebooks, code snippets, and introduces the project team. This primer is part of a series by the Broad Institute of MIT and Harvard, designed to provide in-depth introductions to complex trait genetics topics for a wide audience, from research technicians to established investigators entering the field.