Learn about validating Partial Least Squares (PLS) models in this 26-minute video, focusing on selecting the optimal number of components. Explore the importance of model validation, outlier detection, and regression error measures. Examine predicted versus measured plots and delve into cross-validation techniques, including a detailed look at chemical analyses by six laboratories. Discover a secret trick related to cross-validation and gain insights into rules of thumb for making informed choices when validating PLS models.