Explore treatment options for symptomatic severe primary or degenerative mitral regurgitation (MR) in this 18-minute medical education video. Review transesophageal echocardiography (TEE) imaging in a case of severe degenerative MR, focusing on assessing suitability for MitraClip transcatheter edge-to-edge repair (MTEER). Gain insights into the role of intraprocedural TEE guidance and hemodynamic evaluation for a successful MTEER case. Examine the baseline echocardiogram, treatment guidelines, gradient assessment, and the MTEER procedure itself. Analyze hemodynamics and learn about the Repair MR Trial. Note that this educational program may contain graphic medical content.