Explore the complexities of P-Glycoprotein and drug transport through a comprehensive case study presented by Jomy George. Delve into the NIH Principles of Clinical Pharmacology Course, focusing on rational drug development and therapeutic utilization. Examine a patient case, side effects, and implicated drugs while understanding the mechanism of action and potential drug interactions. Analyze clinical implications, management challenges, and decision-making processes in this 21-minute lecture. Gain valuable insights into resources available and conclude with a summary of key points, enhancing your knowledge of clinical pharmacology as a translational scientific discipline.