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1
Introduction
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Presentation
3
high resolution assays
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footprint shapes
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single base pair resolution
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total counts
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interpretation
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linear mapping
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additive decomposition
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modisco
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how it works
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using bodisco
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TN5 Bias
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Bias corrected profiles
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Bias correction with neural network
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Bias correction in two ways
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Bias correction in actual genomes
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Bias correction genomewide
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Deep left profiles
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Motif discovery
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Summary
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Discussion session
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Highlights
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Variant effect score
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Bias Factorization
Description:
Explore deep learning techniques for genomic discovery in this comprehensive workshop presentation from the Novo Nordisk Foundation Center's Multimodal Data Integration event. Delve into high-resolution assays, footprint shapes, and single base pair resolution as Anshul Kundaje from Stanford University's Departments of Genetics and Computer Science guides you through advanced concepts. Learn about linear mapping, additive decomposition, and the intricacies of MODISCO. Discover the importance of TN5 Bias and various bias correction methods, including neural network approaches and genome-wide applications. Gain insights into deep left profiles, motif discovery, and variant effect scores. Engage with the discussion session highlighting key takeaways and exploring the potential of bias factorization in genomic research.

Deep Learning for Genomic Discovery

Broad Institute
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