Explore the intricacies of harmonizing deeply sequenced genomes in this 37-minute Medical and Population Genetics Primer talk by Zan Koenig from the Broad Institute. Delve into essential topics such as quality control, structural variants, and cloud computing tutorials. Learn about the application of Principal Component Analysis (PCA) through multiple notebook demonstrations. Gain valuable insights into the fundamental principles of complex trait genetics, including human genetic variation, genotyping, and DNA sequencing methods. Benefit from this expert-led session, designed for a diverse audience ranging from research technicians to established investigators entering the field of medical and population genetics.