Explore the intricacies of structural variation in human genomes through this informative 45-minute lecture from the Medical and Population Genetics Primer series at the Broad Institute of MIT and Harvard. Join experts Xuefang Zhao and Emma Pierce-Hoffman as they provide an in-depth introduction to this crucial topic in complex trait genetics. Gain insights into human genetic variation, genotyping, DNA sequencing methods, statistics, and data analysis. Designed for a wide audience, including research technicians, graduate students, postdoctoral fellows, and established investigators entering the field, this freely available video offers valuable knowledge to enhance understanding of medical and population genetics.